Dr. Khalid FERJI - Visible-Light-Driven PET-RAFT Emulsion PISA of

Journal article

Niang Saye, Jihad Oumerri, A. Arteni, J. Six, K. Ferji*
Macromolecular rapid communications, 2025, pp. e00412

Cite

APA Click to copy
Saye, N., Oumerri, J., Arteni, A., Six, J., & Ferji*, K. (2025). Visible-Light-Driven PET-RAFT Emulsion PISA of Biobased Graft Copolymers Toward Spherical Nanoparticle Formulation. Macromolecular Rapid Communications, e00412.

Chicago/Turabian Click to copy
Saye, Niang, Jihad Oumerri, A. Arteni, J. Six, and K. Ferji*. “Visible-Light-Driven PET-RAFT Emulsion PISA of Biobased Graft Copolymers Toward Spherical Nanoparticle Formulation.” Macromolecular rapid communications (2025): e00412.

MLA Click to copy
Saye, Niang, et al. “Visible-Light-Driven PET-RAFT Emulsion PISA of Biobased Graft Copolymers Toward Spherical Nanoparticle Formulation.” Macromolecular Rapid Communications, 2025, p. e00412.

BibTeX Click to copy

@article{niang2025a,
  title = {Visible-Light-Driven PET-RAFT Emulsion PISA of Biobased Graft Copolymers Toward Spherical Nanoparticle Formulation.},
  year = {2025},
  journal = {Macromolecular rapid communications},
  pages = {e00412},
  author = {Saye, Niang and Oumerri, Jihad and Arteni, A. and Six, J. and Ferji*, K.}
}

Abstract

We report the formulation of dextran-based nano-objects via polymerization-induced self-assembly (PISA) in aqueous emulsion, using photoinduced electron/energy transfer RAFT (PET-RAFT) polymerization under visible light irradiation (λ = 500 nm). A dextran macromolecular chain transfer agent (DexCTA), bearing multiple trithiocarbonate groups, was employed as a hydrophilic scaffold for the grafting of poly(methyl methacrylate) (PMMA) chains. Eosin Y was used as a metal-free photocatalyst to mediate polymerization in water under mild conditions. By systematically varying the PMMA graft degree of polymerization (X = 100-400) and solids content (5-15% w/w), we investigated the influence of formulation parameters on nanoparticle morphology and size. High monomer conversion (>99%) was achieved within 2 h of irradiation. Transmission electron microscopy revealed spherical morphologies across all conditions, with increasing particle size as a function of X and solids content. This study highlights the potential of PET-RAFT emulsion PISA as a green and versatile strategy for the design of polymeric nanomaterials.